Article

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

2021-01-25

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) replicates in CD4+ T cells leading to profound T cell loss, immunological dysfunction and AIDS. Determining how HIV-1 shapes the immunological niche in which it resides to create a permissive environment is central to informing efforts to limit pathogenesis, disturb viral reservoirs and achieve a cure. A key roadblock in understanding HIV-T cell interactions is the requi...

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Literature Corpus work: 65985196-42be-57c2-a724-91790d7ba44f
DOI: 10.1101/2021.01.25.428084

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