Article

Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation

2022-08-24

Abstract excerpt

<h4>Background</h4> Tuberculosis (TB) remains a major public health problem globally, even compared to COVID-19. Genome-wide studies have failed to discover genes that explain a large proportion of genetic risk for adult pulmonary TB, and even fewer have examined genetic factors underlying TB severity, an intermediate trait impacting disease experience, quality of life, and risk of mortality. No prior severity ana...

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Literature Corpus work: e224f2d0-f4a0-5da4-8a42-043d357be6e7
DOI: 10.1101/2022.08.23.22279140

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