Article

<i>Mycobacterium tuberculosis</i> genetic features associated with pulmonary tuberculosis severity

2022-05-25

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb) infections result in a wide spectrum of clinical presentations but without proven Mtb genetic determinants. Herein, 234 pulmonary tuberculosis (TB) patients were stratified according to TB disease severity and Mtb genetic features were explored using whole genome sequencing, including heterologous single nucleotide polymorphism (SNP) calling to explore micro-dive...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73622fec-9a5c-51db-a87d-a9a0cf365c10
DOI: 10.1101/2022.05.25.493361

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>Mycobacterium tuberculosis</i> genetic features associated with pulmonary tuberculosis severityDOI 10.1101/2022.05.25.493361Read

Within-host genetic micro-diversity of <i>Mycobacterium tuberculosis</i> and the link with tuberculosis disease featuresSemantic proximity Read

Within-host pathogen population diversity predicts treatment response in TuberculosisSemantic proximity Read

Evolution of <i>Mycobacterium tuberculosis</i> transcription regulation is associated with increased transmission and drug resistanceSemantic proximity Read

Genetic Diversity in Mycobacterium tuberculosis Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease.Semantic proximity Read

The mutational signatures of poor treatment outcomes on the drug-susceptible <i>Mycobacterium tuberculosis</i> genomeSemantic proximity Read

Pan-Genomic Study of Mycobacterium tuberculosis Reflecting the Primary/Secondary Genes, Generality/Individuality, and the Interconversion Through Copy Number VariationsSemantic proximity Read

Understanding the epidemiology and pathogenesis of <i>Mycobacterium tuberculosis</i> with non-redundant pangenome and population geneticsSemantic proximity Read

Pangenome Reconstruction of Mycobacterium tuberculosis as a Guide to Reveal Genomic Features Associated with Strain Clinical PhenotypeSemantic proximity Read

Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammationSemantic proximity Read

Interaction analysis of Mycobacterium tuberculosis between host environment and highly mutated genes from population genetic structure comparisonSemantic proximity Read

Diversity and disease pathogenesis in Mycobacterium tuberculosis.Semantic proximity Read

Understanding Mycobacterium tuberculosis through its genomic diversity and evolutionSemantic proximity Read