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Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler

22 Jan 2021

Abstract excerpt

BACKGROUND: Gene expression signatures have been used as biomarkers of tuberculosis (TB) risk and outcomes. Platforms are needed to simplify access to these signatures and determine their validity in the setting of comorbidities. We developed a computational profiling platform of TB signature gene sets and characterized the diagnostic ability of existing signature gene sets to differentiate active TB from LTBI in...

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PMID: 33482742
DOI: 10.1186/s12879-020-05598-z

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