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Article

The Role of Toll-like Receptor 2 Polymorphisms in Susceptibility to and Severity of Tuberculosis: A Systematic Review.

Pathogens (Basel, Switzerland) - 27 Mar 2026

Sudarto Sudarto, Hafy Zen, Saleh Irsan, Liberty Iche, Ahmad Zen, Lubis Fadhyl Zuhry, Hu Owen, Arista Bryan

Abstract excerpt

Pulmonary tuberculosis (TB) remains a global health threat, with individual genetic determinants like Toll-like receptor 2 (TLR2) gene variations potentially modulating immune responses to Mycobacterium tuberculosis. This systematic review evaluates the role of TLR2 polymorphisms in influencing susceptibility to and clinical manifestations of pulmonary TB. Following PRISMA guidelines, a comprehensive search of...

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Source

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Identifiers

PMID: 42075681
DOI: 10.3390/pathogens15040354
PMCID: PMC13119124

Genes

TLR2

Provenance

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