Article

Genome-wide association study in Brazil identifies genetic susceptibility to tuberculosis with single-cell gene effects

2025-03-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Although genetic factors contribute to tuberculosis (TB) risk, no cross-population causal variants have been identified by genome-wide association studies (GWAS). <h4>Methods</h4> Here, we utilized low-pass whole genome sequencing (lpWGS) with high-pass WGS verified imputation plus detailed epidemiologic risk factors and single-cell expression quantitative loci (sceQTL) to...

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Literature Corpus work: 820e3559-0123-5190-94bc-724223671cac
DOI: 10.1101/2025.03.13.25323932

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