Article
Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains.
mBio - 5 Feb 2025
Akusobi Chidiebere, Choudhery Sanjeevani, Benghomari Bouchra S, Wolf Ian D, Singhvi Shreya, Ioerger Thomas R, Rubin Eric J
Abstract excerpt
Mycobacterium abscessus (Mab) is a clinically significant pathogen and a highly genetically diverse species due to its large accessory genome. The functional consequence of this diversity remains unknown mainly because, to date, functional genomic studies in Mab have been primarily performed on reference strains. Given the growing public health threat of Mab infections, understanding the functional genomic...
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