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Screening of chemical libraries for new antifungal drugs against <i>Aspergillus fumigatus</i> reveals the potential mechanism of action of miltefosine

2021-05-22

Abstract excerpt

Aspergillus fumigatus is an important fungal pathogen and the main etiological agent of aspergillosis, a disease characterized by a noninvasive process that can evolve to a more severe clinical manifestation called invasive pulmonary aspergillosis (IPA) in immunocompromised patients. The antifungal arsenal to threat aspergillosis is very restricted. Azoles are the main therapeutic approach to control IPA, but the...

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Literature Corpus work
e1dd4c77-4d90-5002-897a-60e0265714bf
DOI
10.1101/2021.05.19.444908
Open publication

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Screening of chemical libraries for new antifungal drugs against <i>Aspergillus fumigatus</i> reveals the potential mechanism of action of miltefosineDOI 10.1101/2021.05.19.444908
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