Back to search

Article

The fungal transcription factor SmpR coordinates secondary metabolism and antibacterial defence in <i>Aspergillus fumigatus</i> during interspecies interaction

2026-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Aspergillus fumigatus , an opportunistic human fungal pathogen, encodes numerous secondary metabolite biosynthetic gene clusters (BGCs) that are tightly regulated and often remain silent under standard conditions. Co-cultivation with Streptomyces rapamycinicus or treatment with the secondary metabolite from this species, the arginoketide azalomycin F, induce the otherwise silent fumicycline (...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1293dd8e-defd-5094-9678-7e4028b2a02b
DOI
10.64898/2026.04.05.716574
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The fungal transcription factor SmpR coordinates secondary metabolism and antibacterial defence in <i>Aspergillus fumigatus</i> during interspecies interactionDOI 10.64898/2026.04.05.716574
A network-based model of <i>Aspergillus fumigatus</i> elucidates regulators of development and defensive natural products of an opportunistic pathogenSemantic proximity
Alligamycin A, an unprecedented antifungal β-lactone spiroketal macrolide from <i>Streptomyces iranensis</i>Semantic proximity
Deciphering temporal antifungal dynamics of a rare actinomycete via integrated omicsSemantic proximity
Biosynthesis of Antibacterial Iron-Chelating Tropolones in Aspergillus nidulans as Response to Glycopeptide-Producing StreptomycetesSemantic proximity
Biosynthetic gene clusters, secondary metabolite profiles, and cards of virulence in the closest nonpathogenic relatives of <i>Aspergillus fumigatus</i>Semantic proximity
Bacterium Induces Cryptic Meroterpenoid Pathway in the Pathogenic Fungus <i>Aspergillus fumigatus</i>Semantic proximity
AcuM and AcuK: the global regulators controlling multiple cellular metabolisms in a dimorphic fungus <i>Talaromyces marneffei</i>Semantic proximity
Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensisSemantic proximity
A fungal metabolic regulator underlies infectious synergism during <i>Candida albicans</i> - <i>Staphylococcus</i> aureus intra-abdominal co-infectionSemantic proximity
Heterogeneity in the transcriptional response of the human pathogen <i>Aspergillus fumigatus</i> to the antifungal agent caspofunginSemantic proximity
Characterizing the pathogenic, genomic, and chemical traits of <i>Aspergillus fischeri</i> , a close relative of the major human fungal pathogen <i>Aspergillus fumigatus</i>Semantic proximity
Regulation of gliotoxin biosynthesis and protection in <i>Aspergillus</i> speciesSemantic proximity
Select a neighboring publication to make it the new centre.