Article

Dissecting Metabolic Landscape of Alveolar Macrophage

2023-09-12

Abstract excerpt

The highly plastic nature of Alveolar Macrophage (AM) plays a crucial role in the defense against inhaled particulates and pathogens in the lungs. Depending upon the signal, AM acquires either classically activated M1 phenotype or alternatively activated M2 phenotype. These phenotypes have specific functions and unique metabolic traits such as upregulated glycolysis and pentose phosphate pathway in M1 phase and en...

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Literature Corpus work: 61eb0dd9-28ec-553d-8903-ee2d6e027b9c
DOI: 10.1101/2023.09.08.556783

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