Article

Early IKKβ-dependent anabolic signature governs vascular smooth muscle cells fate and abdominal aortic aneurysm development

2024-06-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Abdominal aortic aneurysm (AAA) is a detrimental disease with no effective pharmacological therapy. While inflammation is recognized as one of the key regulators of AAA, targeting inflammatory pathways once the disease is established does not impact the outcomes. However, understanding the earliest molecular indicators could shed light on the precise biological targets and p...

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Literature Corpus work: e1c9a48f-ca8b-56d4-b3a4-88735b68b85f
DOI: 10.1101/2024.06.12.598763

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