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Article

Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta.

Cardiovascular research - 23 Apr 2021

Zhao Guizhen, Lu Haocheng, Chang Ziyi, Zhao Yang, Zhu Tianqing, Chang Lin, Guo Yanhong, Garcia-Barrio Minerva T, Chen Y Eugene, Zhang Jifeng

Abstract excerpt

AIMS: The artery contains numerous cell types which contribute to multiple vascular diseases. However, the heterogeneity and cellular responses of these vascular cells during abdominal aortic aneurysm (AAA) progression have not been well characterized. METHODS AND RESULTS: Single-cell RNA sequencing was performed on the infrarenal abdominal aortas (IAAs) from C57BL/6J mice at Days 7 and 14 post-sham or...

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Source

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Identifiers

PMID: 32678909
DOI: 10.1093/cvr/cvaa214
PMCID: PMC8064434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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