Article

Epithelial density controls cell migration through an adhesion-nucleus mechanotransduction pathway

2026-04-24

Abstract excerpt

Cell density is thought to regulate tissue growth, homeostasis, and regeneration, yet how cells sense and respond to density remains poorly understood. To investigate density-dependent mechanotransduction, we combined genetically encoded biosensors with quantitative fluorescence microscopy in epithelial cells subjected to genetic, pharmacological, and mechanical perturbations. We found that low epithelial density...

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Literature Corpus work: e1a85839-b8db-5e4d-86e2-e63a82b01fa5
DOI: 10.64898/2026.04.22.720102

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