Article

The nucleocytoplasmic translocation of HINT1 regulates the maturation of cell density

2025-01-14

Abstract excerpt

Cell contact inhibition progresses through three stages: (i) increasing cell density leads to reduced movement while mitosis continues; (ii) a rapid shift to epithelial morphology; and (iii) ongoing division with decreased cell size. This transition involves reorganizing the actin cytoskeleton from stress fibers to a cortical network, stabilizing cell shape, and strengthening cell-cell connections. However, the si...

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Identifiers and source

Literature Corpus work: bd625750-92e8-505f-946a-4a86c0f752c6
DOI: 10.1101/2025.01.13.632869

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