Article

Macrophage-derived FN1 orchestrates the radiation-induced abscopal effect in breast cancer

2026-06-08

Abstract excerpt

<title>Abstract</title> <p>A pivotal objective in clinical research is to transition the abscopal effect in radiotherapy from a stochastic to a deterministic phenomenon. In this study, leveraging a mouse breast cancer model, we discovered that during the manifestation of radiation-induced abscopal effects (RIAE), Fibronectin 1 (FN1) expression experienced a marked downregulation in macrophages within the distant...

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Literature Corpus work: e14a1f1b-d7cc-5fb5-ab5c-392f262c8cf5
DOI: 10.21203/rs.3.rs-9662129/v1

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