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Cancer coopts differentiation of B-cell precursors into macrophages

2021-09-13

Abstract excerpt

<title>Abstract</title> <p>We recently reported that some cancers induce accumulation of bone marrow (BM) B-cell precursors in the spleen to convert them into metastasis-promoting, immunosuppressive B cells. Here, using various murine tumor models and samples from humans with breast and ovarian cancers, we provide evidence that cancer cells also coopt differentiation of the extra nodal B-cell precursors to genera...

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Literature Corpus work
027234de-97a1-5058-be95-c8a4861d00a5
DOI
10.21203/rs.3.rs-858433/v1
Open publication

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Cancer coopts differentiation of B-cell precursors into macrophagesDOI 10.21203/rs.3.rs-858433/v1
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