Article

Cisplatin exposure dysregulates pancreatic islet function in male mice

2024-09-26

Abstract excerpt

Cancer survivors have an increased risk of developing new-onset Type 2 diabetes compared to the general population. Moreover, patients treated with cisplatin, a commonly used chemotherapeutic agent, are more likely to develop metabolic syndrome and Type 2 diabetes compared to age- and sex-matched controls. Insulin-secreting beta cells—located within pancreatic islets—are critical for maintaining glucose homeostasi...

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Literature Corpus work: e1382be4-c8ba-573f-b21e-0988d156160e
DOI: 10.1101/2024.09.25.614996

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