Article

Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice

2020-09-13

Abstract excerpt

<h4>Objective</h4> Human studies consistently show an association between exposure to persistent organic pollutants, including 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD, aka “dioxin”), and increased diabetes risk, but rarely consider potential sex differences. We previously showed that a single high-dose TCDD exposure (20 µg/kg) decreased plasma insulin levels in both male and female mice in vivo , but effect...

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Literature Corpus work: 5fb207ea-a41b-5bcb-b809-8990a86f48c1
DOI: 10.1101/2020.09.12.294587

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