Article

β-cell-specific <i>Ahr</i> expression is critical to high-fat diet-induced hyperinsulinemia

2026-06-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> The aryl hydrocarbon receptor (AhR) pathway primarily mediates pollutant responses by activating xenobiotic metabolism enzymes like cytochrome P450 1A1 and 1A2 (CYP1A). Although AhR has also been implicated in systemic metabolic dysfunction and is inducible in pancreatic islets, its role in islet physiology remains unclear. <h4>Methods</h4> We analyzed a publicly available b...

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Literature Corpus work: 7c3c29d8-f7de-5e5f-8a22-4b156d36782a
DOI: 10.64898/2026.06.25.734641

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