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Therapeutic Strategies for RB1-Deficient Cancers: Intersecting Gene Regulation and Targeted Therapy

2024-03-18

Abstract excerpt

The retinoblastoma (RB) transcriptional corepressor 1 (RB1) is a critical tumor suppressor gene, governing diverse cellular processes implicated in cancer biology. Dysregulation or deletion in RB1 contributes to the development and progression of various cancers, making it a prime target for therapeutic intervention. RB1's canonical function in cell cycle control and DNA repair mechanisms underscores its sign...

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Literature Corpus work
e0b1eee7-da5c-532d-894c-bfdba63725fe
DOI
10.20944/preprints202403.1011.v1
Open publication

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Therapeutic Strategies for RB1-Deficient Cancers: Intersecting Gene Regulation and Targeted TherapyDOI 10.20944/preprints202403.1011.v1
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