Article
Novel insights into RB1 mutation.
Cancer letters - 28 Oct 2022
Yao Yiran, Gu Xiang, Xu Xiaofang, Ge Shengfang, Jia Renbing
Abstract excerpt
Since the discovery of the retinoblastoma susceptibility gene (RB1) decades ago, RB1 has been regarded as a prototype tumor suppressor gene providing a paradigm for tumor genetic research. Constant research has updated the understanding of RB1-related pathways and their impact on tumor and nontumor diseases. Mutation of RB1 gene has been observed in multiple types of malignant tumors including prostate cancer,...
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