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Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer’s-like Pathology in the Hippocampus by Altering the Phenotype of Microglia in APP/PS1 Mouse Model

2020-10-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> There are increasing studies suggest that Traumatic Brain Injury(TBI) might be the cause of some neurodegenerative diseases, including Alzheimer’s Disease(AD). The mechanism of AD induced by TBI has also been elucidated from sorts of aspects. However, there are also researches which opponent to the viewpoint that TBI is the reason of AD. In this study, we invest...

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Literature Corpus work: e0ae77e1-8933-52e7-92a5-0355eedd2072
DOI: 10.21203/rs.3.rs-92179/v1

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Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer’s-like Pathology in the Hippocampus by Altering the Phenotype of Microglia in APP/PS1 Mouse ModelDOI 10.21203/rs.3.rs-92179/v1Read

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