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Article

Accumulation of amyloid in cognitive impairment after mild traumatic brain injury.

Journal of the neurological sciences - 15 Feb 2015

Yang Shun-Tai, Hsiao Ing-Tsung, Hsieh Chia-Ju, Chiang Yung-Hsiao, Yen Tzu-Chen, Chiu Wen-Ta, Lin Kun-Ju, Hu Chaur-Jong

Abstract excerpt

Recent epidemiology studies have indicated that traumatic brain injury (TBI) can increase the risk of developing neurodegenerative diseases such as Alzheimer's disease (AD). Amyloid-β (Aβ) plaques and neurofibrillary tangles are pathological indicators of AD. The accumulation of Aβ is considered the first step of AD pathophysiology. Compelling studies have supported the hypothesis that TBI accelerates the...

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Source

Identifiers

PMID: 25586534
DOI: 10.1016/j.jns.2014.12.032

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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