Article

Clinical-grade whole genome sequencing of colorectal cancer and 3’ transcriptome analysis demonstrate targetable alterations in the majority of patients

2020-05-01

Abstract excerpt

<h4>Introduction</h4> Clinical grade whole genome sequencing (cWGS) has the potential to become standard of care within the clinic because of its breadth of coverage and lack of bias towards certain regions of the genome. Colorectal cancer presents a difficult treatment paradigm, with over 40% of patients presenting at diagnosis with metastatic disease. We hypothesised that cWGS coupled with 3’ transcriptome analy...

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Literature Corpus work: e0a26c39-47d1-5e90-b4be-34e086a83ece
DOI: 10.1101/2020.04.26.20080887

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