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Article

Clinical-grade whole-genome sequencing and 3' transcriptome analysis of colorectal cancer patients.

Genome medicine - 25 Feb 2021

Stodolna Agata, He Miao, Vasipalli Mahesh, Kingsbury Zoya, Becq Jennifer, Stockton Joanne D, Dilworth Mark P, James Jonathan, Sillo Toju, Blakeway Daniel, Ward Stephen T, Ismail Tariq, Ross Mark T, Beggs Andrew D

Abstract excerpt

BACKGROUND: Clinical-grade whole-genome sequencing (cWGS) has the potential to become the standard of care within the clinic because of its breadth of coverage and lack of bias towards certain regions of the genome. Colorectal cancer presents a difficult treatment paradigm, with over 40% of patients presenting at diagnosis with metastatic disease. We hypothesised that cWGS coupled with 3' transcriptome analysis...

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Identifiers

PMID: 33632293
DOI: 10.1186/s13073-021-00852-8
PMCID: PMC7908713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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