Article

Prognostic whole-genome and transcriptome signatures in colorectal cancers

2023-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Colorectal cancer (CRC) is caused by a sequence of somatic genomic alterations affecting driver genes in core cancer pathways 1 . To understand the functional and prognostic impact of cancer-causing somatic mutations, we analysed the whole genomes and transcriptomes of 1,063 primary CRCs in a population-based cohort with long-term follow-up. From the 96 mutated driver genes, 9 were novel to CRC...

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Literature Corpus work: 4adde5a7-ead9-5d66-9138-1186cf5de4a6
DOI: 10.1101/2023.03.28.23287846

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