Article
The Evolving Role of Genomics in Colorectal Cancer.
Clinical oncology (Royal College of Radiologists (Great Britain)) - 1 Jan 2025
Berner A M, Murugaesu N
Abstract excerpt
Approximately 75% of colorectal cancers (CRCs) harbour an identifiable driver mutation, 5% of which are heritable. These drivers have recognised implications for prognosis and therapy selection. In addition, potential germline mutations require investigations to inform testing of relatives, as well as surveillance for other malignancies. With increasing numbers of targeted drugs being approved, judicious testing...
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