Article

Cryo-EM structure of <i>ex vivo</i> fibrils associated with extreme AA amyloidosis prevalence in a cat shelter

2022-05-09

Abstract excerpt

<h4>ABSTRACT</h4> AA amyloidosis is a systemic disease characterized by deposition of misfolded serum amyloid A protein (SAA) into cross-β amyloid in multiple organs in humans and animals. AA amyloidosis occurs at high SAA serum levels during chronic inflammation. The disease can be transmitted horizontally, likely facilitated by prion-like mechanism, in captive animals leading to extreme disease prevalence, e.g....

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Literature Corpus work: e09ca097-c3fa-57fa-a6fc-4294e5ba59c0
DOI: 10.1101/2022.05.09.491126

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