Article

RNA degradation analysis reveals ribosome dynamics in complex microbiome samples

2021-04-10

Abstract excerpt

Post-transcriptional regulation is essential for life, yet we are currently unable to investigate its role in complex microbiome samples. Here we discover that co-translational mRNA degradation, where the degradation machinery follows the last translating ribosome, is conserved across prokaryotes. By investigating 5’P mRNA decay intermediates, we obtain in vivo ribosome protection information that allows the stud...

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Literature Corpus work: 1c81fb86-5c5e-5217-9a57-048fa8ef76f0
DOI: 10.1101/2021.04.08.439066

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