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Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in <i>Drosophila</i>

2025-03-25

Abstract excerpt

In many organisms, including Drosophila and humans, neural progenitors exit the cell cycle and are eliminated by the end of development, thereby restricting adult neurogenesis to specific brain regions. Here, we identify the evolutionarily conserved transcription factor Kruppel (Kr) as a lineage-specific regulator of cell cycle exit and elimination of mushroom body neuroblasts (MBNBs), which generate the learning...

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Identifiers and source

Literature Corpus work
e0197078-8516-551c-8950-d6b620c2a242
DOI
10.1101/2025.03.24.645006
Open publication

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Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in <i>Drosophila</i>DOI 10.1101/2025.03.24.645006
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