Article

Macrophages support healing of ischemic injury by transdifferentiating towards mural cells and adopting functions important for vascular support

2022-11-21

Abstract excerpt

<title>Abstract</title> <p>Sterile inflammation following injury is important for tissue restoration. In injured human and mouse tissues, macrophages were recently found to accumulate perivascularly. This study investigates if macrophages adopt a mural cell identity important for restoration following ischemic injury. Single-cell RNA-sequencing of fate-mapped macrophages from ischemic mouse muscles demonstrates a...

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Literature Corpus work: c84554cc-19d8-5d9d-980e-03ba54f9490d
DOI: 10.21203/rs.3.rs-2263892/v1

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