Article

The Single Cell Landscape of the Human Vein After Arteriovenous Fistula Creation and Implications for Maturation Failure

2025-01-24

Abstract excerpt

<h4>ABSTRACT</h4> The biological mechanisms underlying arteriovenous fistula (AVF) maturation in hemodialysis patients remain poorly understood despite decades of research. To address this gap, we investigated the cellular changes in the venous wall after fistula creation in histological biopsies of longitudinal veins and AVF samples (N=23 patients). Using single-cell RNA sequencing of 70,281 cells from pre-acces...

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Literature Corpus work: 0abd9a09-19e6-5d68-97da-b65732f4fab1
DOI: 10.1101/2025.01.23.634529

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