Article

Single cell RNA sequencing reveals mechanisms underlying a senescence-like phenotype of Alveolar Macrophages during Aging

2022-06-05

Abstract excerpt

<h4>Summary</h4> Alveolar Macrophages (AMs) are unique innate immune cells that reside in the alveolar space and accommodate the ever-changing needs of the lungs against internal and external challenges. During homeostasis, AMs maintain themselves through self-renewal without input from adult hematopoietic stem cells. Currently, little is known regarding the influence of aging on AM dynamics, heterogeneity and tr...

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Literature Corpus work: e008e813-f6de-5771-a55e-c53a9e8174a1
DOI: 10.1101/2022.06.04.494822

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