Article

Lung environment in healthy old age shapes the phenotype and CCR2-mediated recruitment of a subset of apoptotic, high-turnover alveolar macrophages

2025-07-25

Abstract excerpt

<title>Abstract</title> <p>Immune system changes with age lead to chronic systemic inflammation termed "inflammaging", contributing to age-related pathologies. Alveolar macrophages (AMs) maintain lung homeostasis and health. The impact of inflammaging on AM populations requires further definition. Herein, we examined the effect of age on the phenotype and ontogeny of AMs from mice, non-human primates and humans....

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Literature Corpus work: 2b42194f-fa0c-5144-8f30-116e17ea1834
DOI: 10.21203/rs.3.rs-7123735/v1

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