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The Contribution of Macrophage Plasticity to Inflammatory Arthritis and Their Potential as Therapeutic Targets

20 Sept 2024

Abstract excerpt

Inflammatory arthritis are common chronic inflammatory autoimmune diseases characterised by progressive, destructive inflammation of the joints leading to a loss of function and significant comorbidities; importantly, there are no cures and only 20% of patients achieve drug-free remission for over 2 years. Macrophages play a vital role in maintaining homeostasis, however, under the wrong environmental cues,...

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PMID: 39329767
DOI: 10.3390/cells13181586

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