Article

Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study

2021-03-29

Abstract excerpt

Genetic variants identified by genome-wide association studies can contribute to disease risk by altering the production and abundance of mRNA, proteins and other molecules. However, the interplay between molecular intermediaries that define the pathway from genetic variation to disease is not well understood. Here, we evaluated the shared genetic regulation of mRNA molecules, proteins and metabolites derived from...

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Literature Corpus work: dfe7d586-6b1f-58e8-8940-b9f6c41f75f4
DOI: 10.1101/2021.03.26.21254347

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