Article

Complex roles for proliferating cell nuclear antigen in human cytomegalovirus replication

2025-01-06

Abstract excerpt

DNA viruses at once elicit and commandeer host pathways, including DNA repair pathways for virus replication. Despite encoding its own DNA polymerase and processivity factor, human cytomegalovirus (HCMV) recruits the cellular processivity factor, proliferating cell nuclear antigen (PCNA) and specialized host DNA polymerases involved in translesion synthesis (TLS) to replication compartments (RCs) where viral DNA (...

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Literature Corpus work: dfce35ff-bcf3-573e-bd6a-5839c1b9885b
DOI: 10.1101/2025.01.06.631530

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