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Chromatin control of human cytomegalovirus infection

13 Jul 2023

Abstract excerpt

Human cytomegalovirus (HCMV) is a betaherpesvirus that establishes lifelong infection in its host and can cause severe comorbidities in individuals with suppressed or compromised immune systems. The lifecycle of HCMV consists of lytic and latent phases, largely dependent upon the cell type infected and whether transcription from the major immediate early locus can ensue. Control of this locus, which acts as a...

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PMID: 37439556
DOI: 10.1128/mbio.00326-23

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