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Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity

2025-10-19

Abstract excerpt

<h4>ABSTRACT</h4> The DNA damage response (DDR) encompasses a multitude of interconnected pathways that serve as a cellular defense to protect genome integrity. Dysregulation or failure of these pathways results in cancers and genetic disease. DNA viruses, including the herpesvirus cytomegalovirus (CMV), activate DDR signaling during their replicative program. The mechanisms by which they commandeer these respons...

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Identifiers and source

Literature Corpus work
09846913-42e0-5790-8d6e-90596d0d3ee8
DOI
10.1101/2025.10.18.683233
Open publication

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Human cytomegalovirus regulates host DNA repair machinery for viral genome integrityDOI 10.1101/2025.10.18.683233
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