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Article

Work-related factors and risk of amyotrophic lateral sclerosis: A multivariable Mendelian randomization study.

Brain and behavior - 1 Dec 2023

Li Ming, Liao Yile, Luo Zhangkun, Song Hongfei, Yang Zhi

Abstract excerpt

BACKGROUND: The causal relationship between work-related factors and amyotrophic lateral sclerosis (ALS) is unclear. We used a Mendelian randomization (MR) analysis to investigate the unconfounded association between work-related factors and ALS. METHODS: Univariable MR analyses were conducted to evaluate the causal effects of work-related factors on ALS. Instrumental variables from the UK Biobank on work-related...

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Identifiers

PMID: 37960974
DOI: 10.1002/brb3.3317
PMCID: PMC10726785

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