Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide analysis of the heritability of amyotrophic lateral sclerosis.

JAMA neurology - 1 Sept 2014

Keller Margaux F, Ferrucci Luigi, Singleton Andrew B, Tienari Pentti J, Laaksovirta Hannu, Restagno Gabriella, Chiò Adriano, Traynor Bryan J, Nalls Michael A

Abstract excerpt

IMPORTANCE: Considerable advances have been made in our understanding of the genetics underlying amyotrophic lateral sclerosis (ALS). Nevertheless, for the majority of patients who receive a diagnosis of ALS, the role played by genetics is unclear. Further elucidation of the genetic architecture of this disease will help clarify the role of genetic variation in ALS populations. OBJECTIVE: To estimate the relative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Genotype

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25023141
DOI: 10.1001/jamaneurol.2014.1184
PMCID: PMC4566960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide analysis of the heritability of amyotrophic lateral sclerosis.PMID 25023141Read ↗

Genetics of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.Semantic proximity Read ↗

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosisSemantic proximity Read ↗

Lifetime Risk and Heritability of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

A case study of comprehensive association analysis and risk prediction of amyotrophic lateral sclerosis in a Chinese population.Semantic proximity Read ↗

Amyotrophic lateral sclerosis as a complex genetic disease.Semantic proximity Read ↗

Characterising the Genetic Landscape of Amyotrophic Lateral Sclerosis: A Catalogue and Assessment of Over 1,000 Published Genetic VariantsSemantic proximity Read ↗

Genetics of sporadic amyotrophic lateral sclerosisSemantic proximity Read ↗

Dissection of genetic factors associated with amyotrophic lateral sclerosis.Semantic proximity Read ↗

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.Semantic proximity Read ↗

Amyotrophic lateral sclerosis: translating genetic discoveries into therapies.Semantic proximity Read ↗

Partitioning the genetic architecture of amyotrophic lateral sclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.