Back to search

Article

Informatics investigations into HLA-mediated adverse drug reactions

2020-01-01

Abstract excerpt

Adverse drug reactions have been associated with multiple alleles of human leukocyte antigens (HLA) genes for different drugs in different populations. In practice, this means an individual carrying a particular HLA allele has an increased risk of developing an adverse reaction to a certain drug. Computational methods, in particular molecular docking, can be used to improve understanding of the mechanisms involved...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
dfbb7f30-c347-507f-9dc5-3cb2537dbf72
DOI
10.17638/03074372
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Informatics investigations into HLA-mediated adverse drug reactionsDOI 10.17638/03074372
Select a neighboring publication to make it the new centre.