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Article

An update on HLA alleles associated with adverse drug reactions.

Drug metabolism and personalized therapy - 24 May 2017

Fricke-Galindo Ingrid, LLerena Adrián, López-López Marisol

Abstract excerpt

Adverse drug reactions (ADRs) are considered as an important cause of morbidity and mortality. The hypersensitivity reactions are immune-mediated ADRs, which are dose-independent, unpredictable and have been associated with several HLA alleles. The present review aimed to describe HLA alleles that have been associated with different ADRs in populations worldwide, the recommendations of regulatory agencies and...

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PMID: 28315856
DOI: 10.1515/dmpt-2016-0025

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