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A web resource for mining HLA associations with adverse drug reactions: HLA-ADR

1 Jan 2016

Abstract excerpt

Human leukocyte antigens (HLA) are an important family of genes involved in the immune system. Their primary function is to allow the host immune system to be able to distinguish between self and non-self peptides-e.g. derived from invading pathogens. However, these genes have also been implicated in immune-mediated adverse drug reactions (ADRs), presenting a problem to patients, clinicians and pharmaceutical...

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PMID: 27189608
DOI: 10.1093/database/baw069

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