Article

A novel mouse model of cholangiocarcinoma uncovers a role for a SOX17-Tensin 4 pathway in tumor progression

2019-12-10

Abstract excerpt

<h4>Background & Aims</h4> Although earlier diagnosis and treatment of intrahepatic cholangiocarcinoma (iCCA) is necessary to improve therapy, there is still limited information available about initiation and evolution of iCCA precursor lesions. Therefore, there is a need to identify mechanisms driving formation of precancerous lesions and their progression towards invasive tumor using experimental models that fa...

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Literature Corpus work: dfb20c99-f012-5e93-bd52-487edf976272
DOI: 10.1101/870212

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