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Article

Multiple cellular origins and molecular evolution of intrahepatic cholangiocarcinoma.

Cancer letters - 1 Sept 2016

Wei Miaoyan, Lü Lisheng, Lin Peiyi, Chen Zhisheng, Quan Zhiwei, Tang Zhaohui

Abstract excerpt

Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy associated with unfavorable prognosis and for which no effective treatments are available. Its molecular pathogenesis is poorly understood. Genome-wide sequencing and high-throughput technologies have provided critical insights into the molecular basis of ICC while sparking a heated debate on the cellular origin. Cancer exhibits variabilities in...

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PMID: 26940139
DOI: 10.1016/j.canlet.2016.02.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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