Article

Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in <i>Drosophila</i>

2023-09-03

Abstract excerpt

The Amyloid Precursor Protein (APP) is associated with Alzheimer’s disease. Appl is the single Drosophila APP ortholog and is expressed in all neurons throughout development. Appl was previously shown to cell-autonomously modulate axon outgrowth in the mushroom bodies (MBs), the fly olfactory memory center. However, we found that Appl d , the only reported null allele, affects the normal function of vnd , the...

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Literature Corpus work: df93744c-e7be-5d4c-9654-71a267c26785
DOI: 10.1101/2023.09.01.555727

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