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Article

The Drosophila transcript encoded by the β-amyloid protein precursor-like gene is restricted to the nervous system

1 Sept 1990

Abstract excerpt

We have molecularly delineated a Drosophila beta-amyloid protein precursor-like (Appl) gene and analyzed its pattern of expression. Appl defines a new locus within the 1B division of the X-chromosome, a region previously shown to be important for neural development. The genomic limits of the Appl gene were defined by mapping of the Appl cDNAs. The Appl transcript spans approximately 38 kb (1 kb = 10(3)...

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Identifiers

PMID: 2127912
DOI: 10.1242/dev.110.1.185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The Drosophila transcript encoded by the β-amyloid protein precursor-like gene is restricted to the nervous systemPMID 2127912Read ↗

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Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor.Semantic proximity Read ↗

The Drosophila Amyloid Precursor Protein homologue mediates neuronal survival and neuro-glial interactionsSemantic proximity Read ↗

The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactionsSemantic proximity Read ↗

The Drosophila β-Amyloid Precursor Protein Homolog Promotes Synapse Differentiation at the Neuromuscular JunctionSemantic proximity Read ↗

apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor.Semantic proximity Read ↗

Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene.Semantic proximity Read ↗

Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neuronsSemantic proximity Read ↗

Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in <i>Drosophila</i>Semantic proximity Read ↗

<i>Drosophila</i> Amyloid Precursor Protein-Like Is Required for Long-Term MemorySemantic proximity Read ↗

Specific functions of Drosophila amyloid precursor-like protein in the development of nervous system and nonneural tissues.Semantic proximity Read ↗

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