Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

X11/Mint genes control polarized localization of axonal membrane proteins in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 May 2013

Gross Garrett G, Lone G Mohiddin, Leung Lok Kwan, Hartenstein Volker, Guo Ming

Abstract excerpt

Mislocalization of axonal proteins can result in misassembly and/or miswiring of neural circuits, causing disease. To date, only a handful of genes that control polarized localization of axonal membrane proteins have been identified. Here we report that Drosophila X11/Mint proteins are required for targeting several proteins, including human amyloid precursor protein (APP) and Drosophila APP-like protein (APPL),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendrites

Share to Dynamins

Share to Endocytosis

Share to Mushroom Bodies

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 23658195
DOI: 10.1523/JNEUROSCI.5749-12.2013
PMCID: PMC3865514

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

X11/Mint genes control polarized localization of axonal membrane proteins in vivo.PMID 23658195Read ↗

Tight control of the APP-Mint1 interaction in regulating amyloid productionSemantic proximity Read ↗

Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in <i>Drosophila</i>Semantic proximity Read ↗

The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactionsSemantic proximity Read ↗

The Drosophila Amyloid Precursor Protein homologue mediates neuronal survival and neuro-glial interactionsSemantic proximity Read ↗

Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Semantic proximity Read ↗

Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening.Semantic proximity Read ↗

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP SignalingSemantic proximity Read ↗

Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein TargetingSemantic proximity Read ↗

The Drosophila β-Amyloid Precursor Protein Homolog Promotes Synapse Differentiation at the Neuromuscular JunctionSemantic proximity Read ↗

Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction.Semantic proximity Read ↗

Distinct LIN-10 domains are required for its neuronal function, its epithelial function, and its synaptic localization.Semantic proximity Read ↗

Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.