Article

Mapping cell-cell fusion at single-cell resolution

2024-12-14

Abstract excerpt

Cell-cell fusion is a tightly controlled process in the human body known to be involved in fertilization, placental development, muscle growth, bone remodeling, and viral response. Fusion between cancer cells results first in a whole-genome doubled state, which may be followed by the generation of aneuploidies; these genomic alterations are known drivers of tumor evolution. The role of cell-cell fusion in cancer p...

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Literature Corpus work: df921abb-a45d-577a-9d5b-170566f7d8bd
DOI: 10.1101/2024.12.11.627873

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